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Hypoxia-reprogrammed regulatory group 2 innate lymphoid cells promote immunosuppression in pancreatic cancer
BACKGROUND: Previously, we uncovered a patient subgroup with highly malignant pancreatic cancer with serum markers CEA(+)/CA125(+)/CA19-9 ≥ 1000 U/mL (triple-positive, TP). However, the underlying immunosuppressive mechanism in the tumor immune microenvironment (TIME) of this subgroup is still unkno...
Autores principales: | Ye, Longyun, Jin, Kaizhou, Liao, Zhenyu, Xiao, Zhiwen, Xu, Huaxiang, Lin, Xuan, Li, Hao, Li, Tianjiao, Zhang, Wuhu, Han, Xuan, Wang, Wenquan, Gao, Heli, Liu, Liang, Wu, Weiding, Yu, Xianjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117270/ https://www.ncbi.nlm.nih.gov/pubmed/35483273 http://dx.doi.org/10.1016/j.ebiom.2022.104016 |
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