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Synovial mesenchymal progenitor derived aggrecan regulates cartilage homeostasis and endogenous repair capacity

Aggrecan is a critical component of the extracellular matrix of all cartilages. One of the early hallmarks of osteoarthritis (OA) is the loss of aggrecan from articular cartilage followed by degeneration of the tissue. Mesenchymal progenitor cell (MPC) populations in joints, including those in the s...

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Detalles Bibliográficos
Autores principales:	Krawetz, Roman J., Wu, Yiru Elizabeth, Bertram, Karri L., Shonak, Anchita, Masson, Anand O., Ren, Guomin, Leonard, Catherine, Kapoor, Mohit, Matyas, John R., Salo, Paul T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117284/ https://www.ncbi.nlm.nih.gov/pubmed/35585042 http://dx.doi.org/10.1038/s41419-022-04919-1

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