Reduced expression of the psychiatric risk gene DLG2 (PSD93) impairs hippocampal synaptic integration and plasticity

Copy number variants indicating loss of function in the DLG2 gene have been associated with markedly increased risk for schizophrenia, autism spectrum disorder, and intellectual disability. DLG2 encodes the postsynaptic scaffolding protein DLG2 (PSD93) that interacts with NMDA receptors, potassium c...

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Detalles Bibliográficos
Autores principales: Griesius, Simonas, O’Donnell, Cian, Waldron, Sophie, Thomas, Kerrie L., Dwyer, Dominic M., Wilkinson, Lawrence S., Hall, Jeremy, Robinson, Emma S. J., Mellor, Jack R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117295/
https://www.ncbi.nlm.nih.gov/pubmed/35115661
http://dx.doi.org/10.1038/s41386-022-01277-6

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