Prion protein gene mutation detection using long-read Nanopore sequencing

Prion diseases are fatal neurodegenerative conditions that affect humans and animals. Rapid and accurate sequencing of the prion gene PRNP is paramount to human prion disease diagnosis and for animal surveillance programmes. Current methods for PRNP genotyping involve sequencing of small fragments w...

Descripción completa

Detalles Bibliográficos
Autores principales: Kroll, François, Dimitriadis, Athanasios, Campbell, Tracy, Darwent, Lee, Collinge, John, Mead, Simon, Vire, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117325/
https://www.ncbi.nlm.nih.gov/pubmed/35585119
http://dx.doi.org/10.1038/s41598-022-12130-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117325/
https://www.ncbi.nlm.nih.gov/pubmed/35585119
http://dx.doi.org/10.1038/s41598-022-12130-7

Ejemplares similares