Cargando…

Protective Effects of Ginkgolide on a Cellular Model of Alzheimer’s Disease via Suppression of the NF-κB Signaling Pathway

NF-κB signaling has been reported to play a key regulatory role in the pathogenesis of Alzheimer’s disease (AD). The purpose of this study is to investigate the effects of ginkgolide on cell viability in an AD cellular model involving an APP/PS1 double gene-transfected HEK293 cell line (APP/PS1-HEK2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Niu, Tian-Tong, Yin, He, Xu, Bao-Lei, Yang, Ting-Ting, Li, Hui-Qin, Sun, Yi, Liu, Guang-Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117391/ https://www.ncbi.nlm.nih.gov/pubmed/35129804 http://dx.doi.org/10.1007/s12010-022-03828-5

Ejemplares similares

Ginkgolide attenuates memory impairment and neuroinflammation by suppressing the NLRP3/caspase-1 pathway in Alzheimer’s disease
por: Liu, Guang-Zhi, et al.
Publicado: (2023)

Transformation of multi-component ginkgolide into ginkgolide B by Coprinus comatus
por: Ding, HongXue, et al.
Publicado: (2015)

Comparing the role of Ginkgolide B and Ginkgolide K on cultured astrocytes exposed to oxygen-glucose deprivation
por: Yu, Wen-Bo, et al.
Publicado: (2018)

Biosynthesis pathways of ginkgolides
por: Zeng, Zihan, et al.
Publicado: (2013)

Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway
por: Ma, Tianwen, et al.
Publicado: (2022)

Pharmacokinetics of Ginkgolide B after Oral Administration of Three Different Ginkgolide B Formulations in Beagle Dogs
por: Zhao, Jie, et al.
Publicado: (2015)

Ginkgolide C Alleviates Myocardial Ischemia/Reperfusion-Induced Inflammatory Injury via Inhibition of CD40-NF-κB Pathway
por: Zhang, Rui, et al.
Publicado: (2018)

Cardioprotection of Ginkgolide B on Myocardial Ischemia/Reperfusion-Induced Inflammatory Injury via Regulation of A20-NF-κB Pathway
por: Zhang, Rui, et al.
Publicado: (2018)

Ginkgolide B Alleviates Learning and Memory Impairment in Rats With Vascular Dementia by Reducing Neuroinflammation via Regulating NF-κB Pathway
por: Huang, Lijuan, et al.
Publicado: (2021)

Effect of ginkgolide K on calcium channel activity in Alzheimer's disease
por: Liu, Hongbin, et al.
Publicado: (2022)

Neuroregulatory role of ginkgolides
por: Gachowska, Martyna, et al.
Publicado: (2021)

Ginkgolide C Alleviates Acute Lung Injury Caused by Paraquat Poisoning via Regulating the Nrf2 and NF-κB Signaling Pathways
por: Zhang, Rui, et al.
Publicado: (2022)

Ginkgolide B increases hydrogen sulfide and protects against endothelial dysfunction in diabetic rats
por: Wang, Guo-Guang, et al.
Publicado: (2015)

Ginkgolide C attenuates lipopolysaccharide-induced acute lung injury by inhibiting inflammation via regulating the CD40/NF-κB signaling pathway
por: Zhang, Rui, et al.
Publicado: (2021)

Ginkgolide B Protects Against Ischemic Stroke via Targeting AMPK/PINK1
por: Cao, Yile, et al.
Publicado: (2022)

Ginkgolide B preconditioning protects neurons against ischaemia-induced apoptosis
por: Wu, Xiaomei, et al.
Publicado: (2009)

Diterpene Ginkgolides Exert an Antidepressant Effect Through the NT3-TrkA and Ras-MAPK Pathways
por: Wang, Ting, et al.
Publicado: (2020)

Osthole Protects against Acute Lung Injury by Suppressing NF-κB-Dependent Inflammation
por: Jin, Yiyi, et al.
Publicado: (2018)

Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway
por: He, Liuqin, et al.
Publicado: (2017)

Dynamic Balance of Microglia and Astrocytes Involved in the Remyelinating Effect of Ginkgolide B
por: Yin, Jun-Jun, et al.
Publicado: (2020)

Amide Derivatives of Ginkgolide B and Their Inhibitory Effects on PAF-Induced Platelet Aggregation
por: Shang, Qiang, et al.
Publicado: (2021)

Ginkgolide C Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway
por: Liou, Chian-Jiun, et al.
Publicado: (2015)

Andrographolide Suppresses Proliferation of Nasopharyngeal Carcinoma Cells via Attenuating NF-κB Pathway
por: Peng, Tao, et al.
Publicado: (2015)

Ginkgolide A Ameliorates LPS-Induced Inflammatory Responses In Vitro and In Vivo
por: Li, Yan, et al.
Publicado: (2017)

Ginkgolide B Modulates BDNF Expression in Acute Ischemic Stroke
por: Wei, Hu, et al.
Publicado: (2017)

Correction: Zhao, J., et al. Pharmacokinetics of Ginkgolide B after Oral Administration of Three Different Ginkgolide B Formulations in Beagle Dogs. Molecules 2015, 20, 20031–20041
por: Zhao, Jie, et al.
Publicado: (2016)

Optimizing the Formulation for Ginkgolide B Solid Dispersion
por: Wu, Xiao, et al.
Publicado: (2018)

Corrigendum to “Ginkgolide C Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway”
por: Liou, Chian-Jiun, et al.
Publicado: (2017)

Ginkgolides protect against amyloid-β(1–42)-mediated synapse damage in vitro
por: Bate, Clive, et al.
Publicado: (2008)

PXR Mediated Protection against Liver Inflammation by Ginkgolide A in Tetrachloromethane Treated Mice
por: Ye, Nanhui, et al.
Publicado: (2016)

Neuroprotective Effect of Ginkgolide B on Bupivacaine-Induced Apoptosis in SH-SY5Y Cells
por: Li, Le, et al.
Publicado: (2013)

Ginkgolide B Reduces Atherogenesis and Vascular Inflammation in ApoE(−/−) Mice
por: Liu, Xiyun, et al.
Publicado: (2012)

Metabolite-related antidepressant action of diterpene ginkgolides in the prefrontal cortex
por: Hu, Qingchuan, et al.
Publicado: (2018)

Ginkgolide J protects human synovial cells SW982 via suppression of p38-dependent production of pro-inflammatory mediators
por: Zhao, Yujie, et al.
Publicado: (2021)

Ginger extract suppresses the activations of NF-κB and Wnt pathways and protects inflammatory arthritis
por: Öz, Burak, et al.
Publicado: (2022)

Ginsenoside Rg1 Suppresses Type 2 PRRSV Infection via NF-κB Signaling Pathway In Vitro, and Provides Partial Protection against HP-PRRSV in Piglet
por: Yu, Zhi-qing, et al.
Publicado: (2019)

TRIM32 promotes proliferation and confers chemoresistance to breast cancer cells through activation of the NF-κB pathway
por: Zhao, Ting-Ting, et al.
Publicado: (2018)

Ginkgolide B improved postoperative cognitive dysfunction by inhibiting microgliosis-mediated neuroinflammation in the hippocampus of mice
por: Luo, Ting, et al.
Publicado: (2022)

Scopoletin Suppresses Activation of Dendritic Cells and Pathogenesis of Experimental Autoimmune Encephalomyelitis by Inhibiting NF-κB Signaling
por: Zhang, Fei, et al.
Publicado: (2019)

Ginkgolide B promotes neuronal differentiation through the Wnt/β-catenin pathway in neural stem cells of the postnatal mammalian subventricular zone
por: Li, Ming-Yang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_srl1r3i7juivab701c0si8m7ig