Iron accumulation with age alters metabolic pattern and circadian clock gene expression through the reduction of AMP-modulated histone methylation

Iron accumulates with age in mammals, and its possible implications in altering metabolic responses are not fully understood. Here, we report that both high-iron diet and advanced age in mice consistently altered gene expression of many pathways, including those governing the oxidative stress respon...

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Detalles Bibliográficos
Autores principales: Liu, Junhao, Zhao, Yang, Ding, Zhao, Zhao, Yue, Chen, Tingting, Ge, Wenhao, Zhang, Jianfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117543/
https://www.ncbi.nlm.nih.gov/pubmed/35460695
http://dx.doi.org/10.1016/j.jbc.2022.101968

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