mTORC1 regulates high levels of protein synthesis in retinal ganglion cells of adult mice

Mechanistic target of rapamycin (mTOR) and mTOR complex 1 (mTORC1), linchpins of the nutrient sensing and protein synthesis pathways, are present at relatively high levels in the ganglion cell layer (GCL) and retinal ganglion cells (RGCs) of rodent and human retinas. However, the role of mTORCs in t...

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Detalles Bibliográficos
Autores principales: Fort, Patrice E., Losiewicz, Mandy K., Elghazi, Lynda, Kong, Dejuan, Cras-Méneur, Corentin, Fingar, Diane C., Kimball, Scot R., Rajala, Raju V.S., Smith, Alexander J., Ali, Robin R., Abcouwer, Steven F., Gardner, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117545/
https://www.ncbi.nlm.nih.gov/pubmed/35447116
http://dx.doi.org/10.1016/j.jbc.2022.101944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117545/
https://www.ncbi.nlm.nih.gov/pubmed/35447116
http://dx.doi.org/10.1016/j.jbc.2022.101944

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