Nej1 interacts with Sae2 at DNA double-stranded breaks to inhibit DNA resection

The two major pathways of DNA double-strand break repair, nonhomologous end-joining and homologous recombination, are highly conserved from yeast to mammals. The regulation of 5′-DNA resection controls repair pathway choice and influences repair outcomes. Nej1 was first identified as a canonical NHE...

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Detalles Bibliográficos
Autores principales: Mojumdar, Aditya, Adam, Nancy, Cobb, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117546/
https://www.ncbi.nlm.nih.gov/pubmed/35429499
http://dx.doi.org/10.1016/j.jbc.2022.101937

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