Geniposide Possesses the Protective Effect on Myocardial Injury by Inhibiting Oxidative Stress and Ferroptosis via Activation of the Grsf1/GPx4 Axis

Reactive oxygen species (ROS) produced in the ischemic myocardium can induce cardiomyocyte injury and death, resulting in cardiac remodeling. Ferroptosis, known as a newly type of cell death caused by iron-dependent oxidative stress, which is an essential death mechanism in cardiomyocytes. However,...

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Detalles Bibliográficos
Autores principales: Shen, Yuehong, Wang, Xindong, Shen, Xinyu, Wang, Yue, Wang, Shulin, Zhang, Yunyun, Yao, Xiaoming, Xu, Yijiao, Sang, Ming, Pan, Jiamin, Qin, Yu, Zhou, Qian, Shen, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117627/
https://www.ncbi.nlm.nih.gov/pubmed/35600863
http://dx.doi.org/10.3389/fphar.2022.879870

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