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Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING–NF-κB Signaling Pathway

BACKGROUND & AIMS: Sterol regulatory element binding protein cleavage-activating protein (SCAP) is a cholesterol sensor that confers a broad range of functional effects in metabolic diseases. Lean nonalcoholic fatty liver disease (NAFLD) is characterized by a decrease in subcutaneous fat and ect...

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Detalles Bibliográficos
Autores principales:	Huang, Xinyu, Yao, Yingcheng, Hou, Xiaoli, Wei, Li, Rao, Yuhan, Su, Yu, Zheng, Guo, Ruan, Xiong Z., Li, Danyang, Chen, Yaxi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117819/ https://www.ncbi.nlm.nih.gov/pubmed/35367665 http://dx.doi.org/10.1016/j.jcmgh.2022.03.006

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