Cargando…

Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature

The T-tube-directed biliary anastomosis in orthotopic liver transplantation (OLT) aims to minimize preventable biliary complications, including bile leaks and strictures. Biliary complications in patients with OLT increase the risk of morbidity and mortality. This review paper evaluated the current...

Descripción completa

Detalles Bibliográficos
Autores principales: Vest, Mallorie, Ciobanu, Camelia, Nyabera, Akwe, Williams, John, Marck, Matthew, Landry, Ian, Sumbly, Vikram, Iqbal, Saba, Shah, Deesha, Nassar, Mahmoud, Nso, Nso, Rizzo, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117859/
https://www.ncbi.nlm.nih.gov/pubmed/35602800
http://dx.doi.org/10.7759/cureus.24253
_version_ 1784710402530082816
author Vest, Mallorie
Ciobanu, Camelia
Nyabera, Akwe
Williams, John
Marck, Matthew
Landry, Ian
Sumbly, Vikram
Iqbal, Saba
Shah, Deesha
Nassar, Mahmoud
Nso, Nso
Rizzo, Vincent
author_facet Vest, Mallorie
Ciobanu, Camelia
Nyabera, Akwe
Williams, John
Marck, Matthew
Landry, Ian
Sumbly, Vikram
Iqbal, Saba
Shah, Deesha
Nassar, Mahmoud
Nso, Nso
Rizzo, Vincent
author_sort Vest, Mallorie
collection PubMed
description The T-tube-directed biliary anastomosis in orthotopic liver transplantation (OLT) aims to minimize preventable biliary complications, including bile leaks and strictures. Biliary complications in patients with OLT increase the risk of morbidity and mortality. This review paper evaluated the current evidence on the routine use of T-tube reconstruction in OLT cases. A review of prospective, retrospective, observational, cohort studies as well as systematic reviews, meta-analyses, review papers, and opinion papers has been conducted to evaluate the therapeutic potential of T tube-based biliary anastomosis in cases of OLT. Our finding showed a bile leak incidence of 16.6% and 6.6% in T-tube and non-T-tube groups, respectively. The results indicated a lower incidence of anastomotic fistulae in the non-T-tube group (0.6%) compared to the T-tube group (4%). The findings negated statistically significant differences in the three-year actuarial survival rates based on biliary anastomosis with and without T-tube intervention (62.5% vs. 69.8%). The studies revealed a 6-11% and 2-11% incidence of cholangitis in OLT patients with T-tube-based reconstruction and those without a T-tube, respectively, and 26% and 20% incidence of total biliary complications in OLT patients with and without T-tube, respectively. In addition, the findings ruled out the influence of a T-tube on the incidence of perioperative complications, endoscopies, and reoperations in OLT cases. The current evidence correlates the increased incidence of bile leaks, cholangitis, and overall biliary complications with the use of a T-tube during OLT. In addition, T-tube-guided reconstruction has no impact on perioperative complications, overall survival, endoscopies, and reoperations in OLT cases.
format Online
Article
Text
id pubmed-9117859
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-91178592022-05-20 Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature Vest, Mallorie Ciobanu, Camelia Nyabera, Akwe Williams, John Marck, Matthew Landry, Ian Sumbly, Vikram Iqbal, Saba Shah, Deesha Nassar, Mahmoud Nso, Nso Rizzo, Vincent Cureus Internal Medicine The T-tube-directed biliary anastomosis in orthotopic liver transplantation (OLT) aims to minimize preventable biliary complications, including bile leaks and strictures. Biliary complications in patients with OLT increase the risk of morbidity and mortality. This review paper evaluated the current evidence on the routine use of T-tube reconstruction in OLT cases. A review of prospective, retrospective, observational, cohort studies as well as systematic reviews, meta-analyses, review papers, and opinion papers has been conducted to evaluate the therapeutic potential of T tube-based biliary anastomosis in cases of OLT. Our finding showed a bile leak incidence of 16.6% and 6.6% in T-tube and non-T-tube groups, respectively. The results indicated a lower incidence of anastomotic fistulae in the non-T-tube group (0.6%) compared to the T-tube group (4%). The findings negated statistically significant differences in the three-year actuarial survival rates based on biliary anastomosis with and without T-tube intervention (62.5% vs. 69.8%). The studies revealed a 6-11% and 2-11% incidence of cholangitis in OLT patients with T-tube-based reconstruction and those without a T-tube, respectively, and 26% and 20% incidence of total biliary complications in OLT patients with and without T-tube, respectively. In addition, the findings ruled out the influence of a T-tube on the incidence of perioperative complications, endoscopies, and reoperations in OLT cases. The current evidence correlates the increased incidence of bile leaks, cholangitis, and overall biliary complications with the use of a T-tube during OLT. In addition, T-tube-guided reconstruction has no impact on perioperative complications, overall survival, endoscopies, and reoperations in OLT cases. Cureus 2022-04-18 /pmc/articles/PMC9117859/ /pubmed/35602800 http://dx.doi.org/10.7759/cureus.24253 Text en Copyright © 2022, Vest et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Vest, Mallorie
Ciobanu, Camelia
Nyabera, Akwe
Williams, John
Marck, Matthew
Landry, Ian
Sumbly, Vikram
Iqbal, Saba
Shah, Deesha
Nassar, Mahmoud
Nso, Nso
Rizzo, Vincent
Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature
title Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature
title_full Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature
title_fullStr Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature
title_full_unstemmed Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature
title_short Biliary Anastomosis Using T-tube Versus No T-tube for Liver Transplantation in Adults: A Review of Literature
title_sort biliary anastomosis using t-tube versus no t-tube for liver transplantation in adults: a review of literature
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117859/
https://www.ncbi.nlm.nih.gov/pubmed/35602800
http://dx.doi.org/10.7759/cureus.24253
work_keys_str_mv AT vestmallorie biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT ciobanucamelia biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT nyaberaakwe biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT williamsjohn biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT marckmatthew biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT landryian biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT sumblyvikram biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT iqbalsaba biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT shahdeesha biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT nassarmahmoud biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT nsonso biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature
AT rizzovincent biliaryanastomosisusingttubeversusnottubeforlivertransplantationinadultsareviewofliterature