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Gold(III)-P-chirogenic complex induces mitochondrial dysfunction in triple-negative breast cancer

Chemical agents that specifically exploit metabolic vulnerabilities of cancer cells will be beneficial but are rare. The role of oxidative phosphorylation (OXPHOS) in promoting and maintaining triple-negative breast cancer (TNBC) growth provides new treatment opportunity. In this work, we describe A...

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Detalles Bibliográficos
Autores principales: Olelewe, Chibuzor, Kim, Jong Hyun, Ofori, Samuel, Mertens, Randall T., Gukathasan, Sailajah, Awuah, Samuel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117869/
https://www.ncbi.nlm.nih.gov/pubmed/35602949
http://dx.doi.org/10.1016/j.isci.2022.104340