Protocol to induce and assess cGAS-STING pathway activation in vitro

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway plays a pivotal role in several cellular processes including pathogen recognition and inflammatory responses. We describe a protocol to activate the cGAS-STING pathway in murine cells using nucleic acids transfection....

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Detalles Bibliográficos
Autores principales: Chamma, Hanane, Guha, Soumyabrata, Laguette, Nadine, Vila, Isabelle K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9117926/
https://www.ncbi.nlm.nih.gov/pubmed/35600929
http://dx.doi.org/10.1016/j.xpro.2022.101384

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