Temporal and spatially controlled APP transgene expression using Cre-dependent alleles

Although a large number of mouse models have been made to study Alzheimer's disease, only a handful allow experimental control over the location or timing of the protein being used to drive pathology. Other fields have used the Cre and the tamoxifen-inducible CreER driver lines to achieve preci...

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Detalles Bibliográficos
Autores principales: Koller, Emily J., Comstock, Melissa, Bean, Jonathan C., Escobedo, Gabriel, Park, Kyung-Won, Jankowsky, Joanna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118045/
https://www.ncbi.nlm.nih.gov/pubmed/35394029
http://dx.doi.org/10.1242/dmm.049330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118045/
https://www.ncbi.nlm.nih.gov/pubmed/35394029
http://dx.doi.org/10.1242/dmm.049330

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