Cargando…
HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program
BACKGROUND: Lymphatic metastasis has been associated with poor prognosis in bladder cancer patients with limited therapeutic options. Emerging evidence shows that heat shock factor 1 (HSF1) drives diversified transcriptome to promote tumor growth and serves as a promising therapeutic target. However...
Autores principales: | Huang, Ming, Dong, Wen, Xie, Ruihui, Wu, Jilin, Su, Qiao, Li, Wuguo, Yao, Kai, Chen, Yuelong, Zhou, Qianghua, Zhang, Qiang, Li, Wenwen, Cheng, Liang, Peng, Shengmeng, Chen, Siting, Huang, Jian, Chen, Xu, Lin, Tianxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118058/ https://www.ncbi.nlm.nih.gov/pubmed/35434944 http://dx.doi.org/10.1002/cac2.12284 |
Ejemplares similares
-
Targeting WD repeat domain 5 enhances chemosensitivity and inhibits proliferation and programmed death-ligand 1 expression in bladder cancer
por: Zhang, Jingtong, et al.
Publicado: (2021) -
Gene expression profiling of WDR5 regulated genes in bladder cancer
por: Chen, Xu, et al.
Publicado: (2015) -
WD repeat domain 5 promotes chemoresistance and Programmed Death-Ligand 1 expression in prostate cancer
por: Zhou, Qianghua, et al.
Publicado: (2021) -
The PRMT5/WDR77 complex restricts hepatitis E virus replication
por: Ju, Xiaohui, et al.
Publicado: (2023) -
UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer
por: Xiao, Kanghua, et al.
Publicado: (2023)