Cargando…

Distinct cytosine modification profiles define epithelial-to-mesenchymal cell-state transitions

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) is an early step in the invasion-metastasis cascade, involving progression through intermediate cell states. Due to challenges with isolating intermediate cell states, genome-wide cytosine modifications that define transition are not completely...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Min Kyung, Brown, Meredith S, Wilkins, Owen M, Pattabiraman, Diwakar R, Christensen, Brock C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Medicine Ltd 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118069/ https://www.ncbi.nlm.nih.gov/pubmed/35382559 http://dx.doi.org/10.2217/epi-2022-0023

Ejemplares similares

Quantifying the Epithelial-to-Mesenchymal Transition (EMT) from Bench to Bedside
por: Brown, Meredith S., et al.
Publicado: (2022)

Targeting the Epithelial-to-Mesenchymal Transition: The Case for Differentiation-Based Therapy
por: Pattabiraman, Diwakar R., et al.
Publicado: (2017)

Pharmacological Induction of mesenchymal-epithelial transition chemosensitizes breast cancer cells and prevents metastatic progression
por: Bagheri, Meisam, et al.
Publicado: (2023)

Genome-wide characterization of cytosine-specific 5-hydroxymethylation in normal breast tissue
por: Wilkins, Owen M., et al.
Publicado: (2019)

Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer
por: Brown, Meredith S., et al.
Publicado: (2022)

Lineage plasticity enables low-ER luminal tumors to evolve and gain basal-like traits
por: Mohamed, Gadisti Aisha, et al.
Publicado: (2023)

In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition
por: Mitchel, Jennifer A., et al.
Publicado: (2020)

Chemical Methods for Decoding Cytosine Modifications in DNA
por: Booth, Michael J., et al.
Publicado: (2014)

Expression Profiles of Epithelial-Mesenchymal Transition-Associated Proteins in Epithelial Ovarian Carcinoma
por: Kim, Mi-Kyung, et al.
Publicado: (2014)

Epithelial–Mesenchymal Transition Expression Profile Stratifies Human Glioma into Two Distinct Tumor-Immune Subtypes
por: Ren, Changyuan, et al.
Publicado: (2023)

Requirement of Podocalyxin in TGF-Beta Induced Epithelial Mesenchymal Transition
por: Meng, Xiaobo, et al.
Publicado: (2011)

Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
por: Serrano-Gomez, Silvia Juliana, et al.
Publicado: (2016)

TET proteins: on the frenetic hunt for new cytosine modifications
por: Delatte, Benjamin, et al.
Publicado: (2013)

Cytosine modifications modulate the chromatin architecture of transcriptional enhancers
por: Mahé, Elise A., et al.
Publicado: (2017)

Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation
por: An, Jungeun, et al.
Publicado: (2023)

Mesenchymal-to-epithelial transitions require tissue-specific interactions with distinct laminins
por: Pitsidianaki, Ioanna, et al.
Publicado: (2021)

Alteration of DNMT1/DNMT3A by eribulin elicits global DNA methylation changes with potential therapeutic implications for triple-negative breast cancer
por: Bagheri, Meisam, et al.
Publicado: (2023)

Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability
por: Ngo, Thuy T. M., et al.
Publicado: (2016)

Cytosine modifications in the honey bee (Apis mellifera) worker genome
por: Rasmussen, Erik M. K., et al.
Publicado: (2015)

Cytosine base modifications regulate DNA duplex stability and metabolism
por: Rausch, Cathia, et al.
Publicado: (2021)

Meta-Analysis of Gene Expression Signatures Defining the Epithelial to Mesenchymal Transition during Cancer Progression
por: Gröger, Christian J., et al.
Publicado: (2012)

Mapping Structurally Defined Guanine Oxidation Products along DNA Duplexes: Influence of Local Sequence Context and Endogenous Cytosine Methylation
por: Ming, Xun, et al.
Publicado: (2014)

Oxygen and Guanine–Cytosine Profiles in Marine Environments
por: Romero, Héctor, et al.
Publicado: (2009)

Enzymatic approaches for profiling cytosine methylation and hydroxymethylation
por: Wang, Tong, et al.
Publicado: (2021)

Epithelial to Mesenchymal Transition Relevant Subtypes with Distinct Prognosis and Responses to Chemo- or Immunotherapies in Osteosarcoma
por: Zhou, Yang, et al.
Publicado: (2022)

SCAN database: facilitating integrative analyses of cytosine modification and expression QTL
por: Zhang, Wei, et al.
Publicado: (2015)

Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging
por: Oh, Gabriel, et al.
Publicado: (2018)

Epigenetic modification of cytosines fine tunes the stability of i-motif DNA
por: Wright, Elisé P, et al.
Publicado: (2020)

Global analysis of cytosine and adenine DNA modifications across the tree of life
por: Varma, Sreejith Jayasree, et al.
Publicado: (2022)

Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy
por: Jung, Inkyung, et al.
Publicado: (2023)

Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency
por: Mulholland, Christopher B., et al.
Publicado: (2020)

The Epithelial-to-Mesenchymal Transition in Cancer
por: Roche, Joëlle
Publicado: (2018)

Epithelial–mesenchymal transition in cancer
por: Moustakas, Aristidis, et al.
Publicado: (2017)

Cortactin in Epithelial–Mesenchymal Transition
por: Ji, Rong, et al.
Publicado: (2020)

Glycobiology of the Epithelial to Mesenchymal Transition
por: Pucci, Michela, et al.
Publicado: (2021)

Epithelial–Mesenchymal Transition (EMT)
por: Manfioletti, Guidalberto, et al.
Publicado: (2023)

Dynamic Chromatin Modification Sustains Epithelial-Mesenchymal Transition following Inducible Expression of Snail-1
por: Javaid, Sarah, et al.
Publicado: (2013)

Pinin Induces Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating m6A Modification
por: Qiao, Kailiang, et al.
Publicado: (2021)

Histone Modifications Represent a Key Epigenetic Feature of Epithelial-to-Mesenchyme Transition in Pancreatic Cancer
por: Xu, Ying, et al.
Publicado: (2023)

Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial–mesenchymal transition
por: Irie, Hanna Y., et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_14kuqs1o6ustorcv4hsjc9t5lt