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Intratumoral delivery of a novel oncolytic adenovirus encoding human antibody against PD-1 elicits enhanced antitumor efficacy

To date, diverse combination therapies with immune checkpoint inhibitors (ICIs), particularly oncolytic virotherapy, have demonstrated enhanced therapeutic outcomes in cancer treatment. However, high pre-existing immunity against the widely used adenovirus human serotype 5 (AdHu5) limits its extensi...

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Detalles Bibliográficos
Autores principales:	Zhou, Ping, Wang, Xuchen, Xing, Man, Yang, Xi, Wu, Mangteng, Shi, Hongyang, Zhu, Caihong, Wang, Xiang, Guo, Yingying, Tang, Shubing, Huang, Zhong, Zhou, Dongming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118129/ https://www.ncbi.nlm.nih.gov/pubmed/35615266 http://dx.doi.org/10.1016/j.omto.2022.04.007

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