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Efficacy of a third-generation oncolytic herpes simplex virus in refractory soft tissue sarcoma xenograft models

Malignant soft tissue tumors, particularly highly malignant leiomyosarcomas, are resistant to chemotherapy and associated with a poor prognosis. T-01, a third-generation genetically modified herpes simplex virus type 1, replicates in tumor cells alone and exerts a cell-killing effect. The current st...

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Detalles Bibliográficos
Autores principales:	Hatta, Masahiko, Kaibori, Masaki, Matsushima, Hideyuki, Yoshida, Terufumi, Okumura, Tadayoshi, Hayashi, Mikio, Yoshii, Kengo, Todo, Tomoki, Sekimoto, Mitsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118137/ https://www.ncbi.nlm.nih.gov/pubmed/35615265 http://dx.doi.org/10.1016/j.omto.2022.04.010

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