Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators

[Image: see text] P-glycoprotein (Pgp), an ATP binding cassette (ABC) transporter, is an ATP-dependent efflux pump responsible for cancer multidrug resistance. As part of efforts to identify human Pgp (hPgp) inhibitors, we prepared a series of novel triazole-conjugated dihydropyrimidinones using a s...

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Detalles Bibliográficos
Autores principales: Bijani, Sabera, Shaikh, Faraz, Mirza, Sheefa, Weng In Siu, Shirley, Jain, Nayan, Rawal, Rakesh, Richards, Nigel G. J., Shah, Anamik, Radadiya, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118204/
https://www.ncbi.nlm.nih.gov/pubmed/35601326
http://dx.doi.org/10.1021/acsomega.1c05839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118204/
https://www.ncbi.nlm.nih.gov/pubmed/35601326
http://dx.doi.org/10.1021/acsomega.1c05839

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