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Novel Dihydropyrimidinone Derivatives as Potential P-Glycoprotein Modulators
[Image: see text] P-glycoprotein (Pgp), an ATP binding cassette (ABC) transporter, is an ATP-dependent efflux pump responsible for cancer multidrug resistance. As part of efforts to identify human Pgp (hPgp) inhibitors, we prepared a series of novel triazole-conjugated dihydropyrimidinones using a s...
Autores principales: | Bijani, Sabera, Shaikh, Faraz, Mirza, Sheefa, Weng In Siu, Shirley, Jain, Nayan, Rawal, Rakesh, Richards, Nigel G. J., Shah, Anamik, Radadiya, Ashish |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118204/ https://www.ncbi.nlm.nih.gov/pubmed/35601326 http://dx.doi.org/10.1021/acsomega.1c05839 |
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