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Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care

OBJECTIVE: To analyze the evolution of the stages of CKD and the progression of the estimation of glomerular filtration rate (eGFR) in patients with newly diagnosed hypertension. DESIGN: Retrospective cohort. SITE: Family Medicine Unit No. 31, Mexican Social Security Institute, Mexico City. PARTICIP...

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Autores principales: Figueroa-García, Juan, Granados-García, Víctor, Hernández-Rivera, Juan Carlos H., Lagunes-Cisneros, Montserrat, Alvarado-Gutiérrez, Teresa, Paniagua-Sierra, José Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118352/
https://www.ncbi.nlm.nih.gov/pubmed/35576888
http://dx.doi.org/10.1016/j.aprim.2022.102364
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author Figueroa-García, Juan
Granados-García, Víctor
Hernández-Rivera, Juan Carlos H.
Lagunes-Cisneros, Montserrat
Alvarado-Gutiérrez, Teresa
Paniagua-Sierra, José Ramón
author_facet Figueroa-García, Juan
Granados-García, Víctor
Hernández-Rivera, Juan Carlos H.
Lagunes-Cisneros, Montserrat
Alvarado-Gutiérrez, Teresa
Paniagua-Sierra, José Ramón
author_sort Figueroa-García, Juan
collection PubMed
description OBJECTIVE: To analyze the evolution of the stages of CKD and the progression of the estimation of glomerular filtration rate (eGFR) in patients with newly diagnosed hypertension. DESIGN: Retrospective cohort. SITE: Family Medicine Unit No. 31, Mexican Social Security Institute, Mexico City. PARTICIPANTS: Patients with hypertension who have been diagnosed in primary care and have developed chronic kidney disease. MAIN MEASUREMENTS: The eGFR was calculated with the CKD Epi formula in three moments, the first measurement was at the time of diagnosis of hypertension, the second measurement was made when it arrived a change in CKD stage and the last one at the end of the study, with which the evolution time from one stage to another was obtained, as well as the drop in eGFR. RESULTS: The sample consisted of 207 electronic health records of patients, with an average follow-up of 10.2 years from the moment of diagnosis of hypertension until the end of the study. The average time to go from one baseline stage of CKD to another was 7 years (average decline in eGFR of 5.8 ml/min/year) and to have a second stage change was 3.2 years (average decline in eGFR of 6.8 ml/min/year), with a statistically significant repeated measures ANOVA (p < 0.001). CONCLUSIONS: Patients with newly diagnosed hypertension remain longer in the initial stages of CKD, to later evolve and change more quickly.
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spelling pubmed-91183522022-05-20 Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care Figueroa-García, Juan Granados-García, Víctor Hernández-Rivera, Juan Carlos H. Lagunes-Cisneros, Montserrat Alvarado-Gutiérrez, Teresa Paniagua-Sierra, José Ramón Aten Primaria Original Article OBJECTIVE: To analyze the evolution of the stages of CKD and the progression of the estimation of glomerular filtration rate (eGFR) in patients with newly diagnosed hypertension. DESIGN: Retrospective cohort. SITE: Family Medicine Unit No. 31, Mexican Social Security Institute, Mexico City. PARTICIPANTS: Patients with hypertension who have been diagnosed in primary care and have developed chronic kidney disease. MAIN MEASUREMENTS: The eGFR was calculated with the CKD Epi formula in three moments, the first measurement was at the time of diagnosis of hypertension, the second measurement was made when it arrived a change in CKD stage and the last one at the end of the study, with which the evolution time from one stage to another was obtained, as well as the drop in eGFR. RESULTS: The sample consisted of 207 electronic health records of patients, with an average follow-up of 10.2 years from the moment of diagnosis of hypertension until the end of the study. The average time to go from one baseline stage of CKD to another was 7 years (average decline in eGFR of 5.8 ml/min/year) and to have a second stage change was 3.2 years (average decline in eGFR of 6.8 ml/min/year), with a statistically significant repeated measures ANOVA (p < 0.001). CONCLUSIONS: Patients with newly diagnosed hypertension remain longer in the initial stages of CKD, to later evolve and change more quickly. Elsevier 2022-07 2022-05-13 /pmc/articles/PMC9118352/ /pubmed/35576888 http://dx.doi.org/10.1016/j.aprim.2022.102364 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Figueroa-García, Juan
Granados-García, Víctor
Hernández-Rivera, Juan Carlos H.
Lagunes-Cisneros, Montserrat
Alvarado-Gutiérrez, Teresa
Paniagua-Sierra, José Ramón
Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
title Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
title_full Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
title_fullStr Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
title_full_unstemmed Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
title_short Evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
title_sort evolution of the stage of chronic kidney disease from the diagnosis of hypertension in primary care
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118352/
https://www.ncbi.nlm.nih.gov/pubmed/35576888
http://dx.doi.org/10.1016/j.aprim.2022.102364
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