Treatment of experimental autoimmune encephalomyelitis using AAV gene therapy by blocking T cell costimulatory pathways

Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS), characterized by inflammation and demyelination. Presently, repeated relapses of MS necessitate long-term immune-regulatory therapy. Blocking the CD28-B7 and CD40-CD40L costimulatory pathways is an effective...

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Detalles Bibliográficos
Autores principales: Zhong, Chen, Chen, Zifeng, Xia, Yong, Wu, Jun, Zhang, Feixu, Cheng, Cheng, Wu, Xia, Zhuang, Yingping, Xiao, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118358/
https://www.ncbi.nlm.nih.gov/pubmed/35615707
http://dx.doi.org/10.1016/j.omtm.2022.04.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118358/
https://www.ncbi.nlm.nih.gov/pubmed/35615707
http://dx.doi.org/10.1016/j.omtm.2022.04.011

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