Synthesis, molecular docking, and cytotoxicity of quinazolinone and dihydroquinazolinone derivatives as cytotoxic agents

BACKGROUND: Cancer is the most cause of morbidity and mortality, and a major public health problem worldwide. In this context, two series of quinazolinone 5a–e and dihydroquinazolinone 10a–f compounds were designed, synthesized as cytotoxic agents. METHODOLOGY: All derivatives (5a–e and 10a–f) were...

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Detalles Bibliográficos
Autores principales: Taayoshi, Fahimeh, Iraji, Aida, Moazzam, Ali, Soleimani, Meysam, Asadi, Mehdi, Pedrood, Keyvan, Akbari, Mosayeb, Salehabadi, Hafezeh, Larijani, Bagher, Adibpour, Neda, Mahdavi, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118628/
https://www.ncbi.nlm.nih.gov/pubmed/35585608
http://dx.doi.org/10.1186/s13065-022-00825-x

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