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Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis
BACKGROUND: Rheumatoid arthritis (RA) is a chronic, immune-mediated inflammatory disease of the joints that has been associated with variation in the peripheral blood methylome. In this study, we aim to identify epigenetic variation that is associated with the response to tumor necrosis factor inhib...
Autores principales: | Julià, Antonio, Gómez, Antonio, López-Lasanta, María, Blanco, Francisco, Erra, Alba, Fernández-Nebro, Antonio, Mas, Antonio Juan, Pérez-García, Carolina, Vivar, Ma Luz García, Sánchez-Fernández, Simón, Alperi-López, Mercedes, Sanmartí, Raimon, Ortiz, Ana María, Fernandez-Cid, Carlos Marras, Díaz-Torné, César, Moreno, Estefania, Li, Tianlu, Martínez-Mateu, Sergio H., Absher, Devin M., Myers, Richard M., Molina, Jesús Tornero, Marsal, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118662/ https://www.ncbi.nlm.nih.gov/pubmed/35576644 http://dx.doi.org/10.1016/j.ebiom.2022.104053 |
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