G-CSF upregulates the expression of aquaporin-9 through CEBPB to enhance the cytotoxic activity of arsenic trioxide to acute myeloid leukemia cells

BACKGROUND: Arsenic trioxide (ATO) is highly effective in acute promyelocytic leukemia (APL) patients, but it fails to show satisfactory efficacy in other acute myeloid leukemia (AML) patients with non-APL subtypes. Different from the APL cells, most non-APL AML cells express low levels of the ATO t...

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Autores principales: Fu, Wanbin, Zhu, Gelan, Xu, Lan, Liu, Jia, Han, Xiaofeng, Wang, Junying, Wang, Xinpeng, Hou, Jian, Zhao, Huanbin, Zhong, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118687/
https://www.ncbi.nlm.nih.gov/pubmed/35590355
http://dx.doi.org/10.1186/s12935-022-02613-y

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