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Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong

BACKGROUND: Hypertension is strongly associated with cardiovascular events. Studies have shown that electrocardiographic (ECG) abnormalities were associated with increased risks for cardiovascular events. However local data is limited. The objectives of this study were: (1) to determine the prevalen...

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Autores principales: Tin, Yuen Ying, Chan, Lit Ping, Sung, Jonathan Gabriel, Leung, Shuk Yun, Hui, Eric Ming Tung, Leung, Maria Kwan Wa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118877/
https://www.ncbi.nlm.nih.gov/pubmed/35585508
http://dx.doi.org/10.1186/s12872-022-02662-1
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author Tin, Yuen Ying
Chan, Lit Ping
Sung, Jonathan Gabriel
Leung, Shuk Yun
Hui, Eric Ming Tung
Leung, Maria Kwan Wa
author_facet Tin, Yuen Ying
Chan, Lit Ping
Sung, Jonathan Gabriel
Leung, Shuk Yun
Hui, Eric Ming Tung
Leung, Maria Kwan Wa
author_sort Tin, Yuen Ying
collection PubMed
description BACKGROUND: Hypertension is strongly associated with cardiovascular events. Studies have shown that electrocardiographic (ECG) abnormalities were associated with increased risks for cardiovascular events. However local data is limited. The objectives of this study were: (1) to determine the prevalence of major electrocardiographic abnormalities in patients with hypertension in primary care in Hong Kong, and (2) to determine the association of major electrocardiographic abnormalities with patients’ socio-economical background, cardiovascular disease and cardiovascular risk factors. METHODS: This was a cross-sectional study. Subjects were hypertensive patients aged between 18 and 80 who were enrolled in the Risk Assessment and Management Programme (RAMP) in a general outpatient clinic in Hong Kong. Outcome measures were prevalence of probable ischaemic heart disease (IHD), complete left bundle branch block (LBBB), left ventricular hypertrophy (LVH) and atrial fibrillation (AF) in patients with hypertension. The Pearson Chi-square test, independent t-test and Mantel–Haenszel test were used to measure the association between socioeconomic characteristics and cardiovascular risk factors, and ECG abnormalities. RESULTS: 504 hypertensive patients aged 18–80 were recruited in a general outpatient clinic. 6.3% had probable IHD, 0.4% had complete LBBB, 4.0% had LVH and 1.0% had AF. Probable IHD was associated with smoking (P = 0.032), hypercholesterolaemia (P = 0.037) and higher 10-year CV risk (P = 0.04). Complete LBBB was associated with smoking (P = 0.021) and hypercholesterolaemia (P = 0.022). LVH was associated with male gender (P = 0.001) and longer duration of hypertension (P = 0.035). AF was not significantly associated with any of the clinical or sociodemographic parameters. CONCLUSIONS: This study showed that a significant proportion of patients with hypertension at the primary care setting in Hong Kong had probable ischaemic heart disease, left ventricular hypertrophy and atrial fibrillation. This finding is consistent with both overseas data and historic data in Hong Kong. The detection of electrocardiographic abnormalities is helpful in hypertension management by improving risk stratification. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02662-1.
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spelling pubmed-91188772022-05-20 Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong Tin, Yuen Ying Chan, Lit Ping Sung, Jonathan Gabriel Leung, Shuk Yun Hui, Eric Ming Tung Leung, Maria Kwan Wa BMC Cardiovasc Disord Research BACKGROUND: Hypertension is strongly associated with cardiovascular events. Studies have shown that electrocardiographic (ECG) abnormalities were associated with increased risks for cardiovascular events. However local data is limited. The objectives of this study were: (1) to determine the prevalence of major electrocardiographic abnormalities in patients with hypertension in primary care in Hong Kong, and (2) to determine the association of major electrocardiographic abnormalities with patients’ socio-economical background, cardiovascular disease and cardiovascular risk factors. METHODS: This was a cross-sectional study. Subjects were hypertensive patients aged between 18 and 80 who were enrolled in the Risk Assessment and Management Programme (RAMP) in a general outpatient clinic in Hong Kong. Outcome measures were prevalence of probable ischaemic heart disease (IHD), complete left bundle branch block (LBBB), left ventricular hypertrophy (LVH) and atrial fibrillation (AF) in patients with hypertension. The Pearson Chi-square test, independent t-test and Mantel–Haenszel test were used to measure the association between socioeconomic characteristics and cardiovascular risk factors, and ECG abnormalities. RESULTS: 504 hypertensive patients aged 18–80 were recruited in a general outpatient clinic. 6.3% had probable IHD, 0.4% had complete LBBB, 4.0% had LVH and 1.0% had AF. Probable IHD was associated with smoking (P = 0.032), hypercholesterolaemia (P = 0.037) and higher 10-year CV risk (P = 0.04). Complete LBBB was associated with smoking (P = 0.021) and hypercholesterolaemia (P = 0.022). LVH was associated with male gender (P = 0.001) and longer duration of hypertension (P = 0.035). AF was not significantly associated with any of the clinical or sociodemographic parameters. CONCLUSIONS: This study showed that a significant proportion of patients with hypertension at the primary care setting in Hong Kong had probable ischaemic heart disease, left ventricular hypertrophy and atrial fibrillation. This finding is consistent with both overseas data and historic data in Hong Kong. The detection of electrocardiographic abnormalities is helpful in hypertension management by improving risk stratification. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12872-022-02662-1. BioMed Central 2022-05-18 /pmc/articles/PMC9118877/ /pubmed/35585508 http://dx.doi.org/10.1186/s12872-022-02662-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Tin, Yuen Ying
Chan, Lit Ping
Sung, Jonathan Gabriel
Leung, Shuk Yun
Hui, Eric Ming Tung
Leung, Maria Kwan Wa
Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong
title Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong
title_full Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong
title_fullStr Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong
title_full_unstemmed Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong
title_short Prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in Hong Kong
title_sort prevalence of major electrocardiographic abnormalities in patients with hypertension in a primary care clinic in hong kong
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118877/
https://www.ncbi.nlm.nih.gov/pubmed/35585508
http://dx.doi.org/10.1186/s12872-022-02662-1
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