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Identification of microRNA-mRNA regulatory network associated with oxidative DNA damage in human astrocytes

The high lipid content of the brain, coupled with its heavy oxygen dependence and relatively weak antioxidant system, makes it highly susceptible to oxidative DNA damage that contributes to neurodegeneration. This study is aimed at identifying specific ROS-responsive miRNAs that modulate the express...

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Detalles Bibliográficos
Autores principales: Nwokwu, Chukwumaobim Daniel, Xiao, Adam Y., Harrison, Lynn, Nestorova, Gergana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118907/
https://www.ncbi.nlm.nih.gov/pubmed/35570825
http://dx.doi.org/10.1177/17590914221101704