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Identification of microRNA-mRNA regulatory network associated with oxidative DNA damage in human astrocytes
The high lipid content of the brain, coupled with its heavy oxygen dependence and relatively weak antioxidant system, makes it highly susceptible to oxidative DNA damage that contributes to neurodegeneration. This study is aimed at identifying specific ROS-responsive miRNAs that modulate the express...
Autores principales: | Nwokwu, Chukwumaobim Daniel, Xiao, Adam Y., Harrison, Lynn, Nestorova, Gergana G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118907/ https://www.ncbi.nlm.nih.gov/pubmed/35570825 http://dx.doi.org/10.1177/17590914221101704 |
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