TIGAR alleviates oxidative stress in brain with extended ischemia via a pentose phosphate pathway-independent manner

TP53-induced glycolysis and apoptosis regulator (TIGAR) alleviates oxidative stress and protects against ischemic neuronal injury by shifting glucose metabolism into the pentose phosphate pathway (PPP). However, the brain alters glucose metabolism from PPP to glycolysis during prolonged ischemia. It...

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Detalles Bibliográficos
Autores principales: Liu, Mengru, Zhou, Xinyu, Li, Yue, Ma, Shijia, Pan, Ling, Zhang, Xingxian, Zheng, Wanqing, Wu, Zhanxun, Wang, Ke, Ahsan, Anil, Wu, Jiaying, Jiang, Lei, Lu, Yangyang, Hu, Weiwei, Qin, Zhenghong, Chen, Zhong, Zhang, Xiangnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9118922/
https://www.ncbi.nlm.nih.gov/pubmed/35576689
http://dx.doi.org/10.1016/j.redox.2022.102323

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