Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening

The emergence of several zoonotic viruses in the last twenty years, especially the pandemic outbreak of SARS-CoV-2, has exposed a dearth of antiviral drug therapies for viruses with pandemic potential. Developing a diverse drug portfolio will be critical to rapidly respond to novel coronaviruses (Co...

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Detalles Bibliográficos
Autores principales: Roy, Anu, Alhammad, Yousef M., McDonald, Peter, Johnson, David K., Zhuo, Junlin, Wazir, Sarah, Ferraris, Dana, Lehtiö, Lari, Leung, Anthony K.L., Fehr, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119168/
https://www.ncbi.nlm.nih.gov/pubmed/35598780
http://dx.doi.org/10.1016/j.antiviral.2022.105344

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