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Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine

The coronavirus disease of 2019 (COVID-19) pandemic is caused by a novel coronavirus SARS-Cov-2. Four major vaccine types are being used to fight against this deadly pandemic and save precious human lives. All types of vaccines have been associated with a risk of neurological complications ranging f...

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Detalles Bibliográficos
Autores principales: Algahtani, Hussein A., Shirah, Bader H., Alwafi, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119169/
https://www.ncbi.nlm.nih.gov/pubmed/35605509
http://dx.doi.org/10.1016/j.clineuro.2022.107304
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author Algahtani, Hussein A.
Shirah, Bader H.
Alwafi, Emad
author_facet Algahtani, Hussein A.
Shirah, Bader H.
Alwafi, Emad
author_sort Algahtani, Hussein A.
collection PubMed
description The coronavirus disease of 2019 (COVID-19) pandemic is caused by a novel coronavirus SARS-Cov-2. Four major vaccine types are being used to fight against this deadly pandemic and save precious human lives. All types of vaccines have been associated with a risk of neurological complications ranging from mild to severe. Cervical dystonia occurring after a COVID-19 vaccine was not previously reported in the literature. In this article, we describe a case of acute cervical dystonia occurring after the first dose of the BNT162b2 COVID-19 vaccine. We attribute the occurrence of cervical dystonia to the vaccine due to the temporal relationship. This report adds to the literature a possible rare side effect of a COVID-19 vaccine and contributes to the limited literature on potential neurological side effects of mRNA-based vaccines. The likely mechanism is autoimmune. Further research is needed to probe and study the exact mechanism.
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spelling pubmed-91191692022-05-20 Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine Algahtani, Hussein A. Shirah, Bader H. Alwafi, Emad Clin Neurol Neurosurg Case Report The coronavirus disease of 2019 (COVID-19) pandemic is caused by a novel coronavirus SARS-Cov-2. Four major vaccine types are being used to fight against this deadly pandemic and save precious human lives. All types of vaccines have been associated with a risk of neurological complications ranging from mild to severe. Cervical dystonia occurring after a COVID-19 vaccine was not previously reported in the literature. In this article, we describe a case of acute cervical dystonia occurring after the first dose of the BNT162b2 COVID-19 vaccine. We attribute the occurrence of cervical dystonia to the vaccine due to the temporal relationship. This report adds to the literature a possible rare side effect of a COVID-19 vaccine and contributes to the limited literature on potential neurological side effects of mRNA-based vaccines. The likely mechanism is autoimmune. Further research is needed to probe and study the exact mechanism. Elsevier B.V. 2022-07 2022-05-19 /pmc/articles/PMC9119169/ /pubmed/35605509 http://dx.doi.org/10.1016/j.clineuro.2022.107304 Text en © 2022 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Algahtani, Hussein A.
Shirah, Bader H.
Alwafi, Emad
Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
title Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
title_full Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
title_fullStr Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
title_full_unstemmed Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
title_short Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
title_sort acute cervical dystonia following the bnt162b2 mrna covid-19 vaccine
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119169/
https://www.ncbi.nlm.nih.gov/pubmed/35605509
http://dx.doi.org/10.1016/j.clineuro.2022.107304
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