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Deconvolution of malignant pleural effusions immune landscape unravels a novel macrophage signature associated with worse clinical outcome in lung adenocarcinoma patients
BACKGROUND: Immune checkpoint inhibitors are still unable to provide clinical benefit to the large majority of non-small cell lung cancer (NSCLC) patients. A deeper characterization of the tumor immune microenvironment (TIME) is expected to shed light on the mechanisms of cancer immune evasion and r...
Autores principales: | Bruschini, Sara, Pallocca, Matteo, Sperandio, Eleonora, D’Ambrosio, Lorenzo, Ascenzi, Francesca, De Vitis, Claudia, Salvati, Valentina, Esposito, Antonella, Di Martino, Simona, De Nicola, Francesca, Paolini, Francesca, Fattore, Luigi, Alessandrini, Gabriele, Facciolo, Francesco, Foddai, Maria Laura, Bassi, Massimiliano, Venuta, Federico, D’Ascanio, Michela, Ricci, Alberto, D’ Andrilli, Antonio, Napoli, Christian, Aurisicchio, Luigi, Fanciulli, Maurizio, Rendina, Erino Angelo, Ciliberto, Gennaro, Mancini, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119185/ https://www.ncbi.nlm.nih.gov/pubmed/35584864 http://dx.doi.org/10.1136/jitc-2021-004239 |
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