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Effect of pH on stability of dimer structure of the main protease of coronavirus-2
The viral main protease (M(pro)) from a novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a key enzyme essential for viral replication and has become an attractive target for antiviral drug development. The M(pro) forms a functional dimer and exhibits a pH-dependent enzyme activi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119281/ https://www.ncbi.nlm.nih.gov/pubmed/35635893 http://dx.doi.org/10.1016/j.bpc.2022.106829 |