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15-PGDH regulates hematopoietic and gastrointestinal fitness during aging

Emerging evidence implicates the eicosanoid molecule prostaglandin E2 (PGE2) in conferring a regenerative phenotype to multiple organ systems following tissue injury. As aging is in part characterized by loss of tissue stem cells’ regenerative capacity, we tested the hypothesis that the prostaglandi...

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Detalles Bibliográficos
Autores principales: Ho, Won Jin, Smith, Julianne N. P., Park, Young Soo, Hadiono, Matthew, Christo, Kelsey, Jogasuria, Alvin, Zhang, Yongyou, Broncano, Alyssia V., Kasturi, Lakshmi, Dawson, Dawn M., Gerson, Stanton L., Markowitz, Sanford D., Desai, Amar B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119474/
https://www.ncbi.nlm.nih.gov/pubmed/35587945
http://dx.doi.org/10.1371/journal.pone.0268787