The host inflammatory response contributes to disease severity in Crimean-Congo hemorrhagic fever virus infected mice

Crimean-Congo hemorrhagic fever virus (CCHFV) is an important human pathogen. In cell culture, CCHFV is sensed by the cytoplasmic RNA sensor retinoic acid-inducible gene I (RIG-I) molecule and its adaptor molecule mitochondrial antiviral signaling (MAVS) protein. MAVS initiates both type I interfero...

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Detalles Bibliográficos
Autores principales: Golden, Joseph W., Zeng, Xiankun, Cline, Curtis R., Smith, Jeffrey M., Daye, Sharon P., Carey, Brian D., Blancett, Candace D., Shoemaker, Charles J., Liu, Jun, Fitzpatrick, Collin J., Stefan, Christopher P., Garrison, Aura R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119488/
https://www.ncbi.nlm.nih.gov/pubmed/35587473
http://dx.doi.org/10.1371/journal.ppat.1010485

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