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Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda
BACKGROUND: Young psychoactive substance users exhibit high-risk behaviours such as unprotected sexual intercourse, and sharing needles and syringes, which increases their risk of Hepatitis B infection. However, there is limited evidence of screening, and vaccination status of this subgroup. The aim...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119510/ https://www.ncbi.nlm.nih.gov/pubmed/35588113 http://dx.doi.org/10.1371/journal.pone.0267953 |
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author | Ssekamatte, Tonny Isunju, John Bosco Mutyoba, Joan Nankya Tetui, Moses Mugambe, Richard K. Nalugya, Aisha Kansiime, Winnifred K. Kitchen, Chenai Brenda, Wagaba Oputan, Patience Bukenya, Justine Nnakate Buregyeya, Esther Kibira, Simon P. S. |
author_facet | Ssekamatte, Tonny Isunju, John Bosco Mutyoba, Joan Nankya Tetui, Moses Mugambe, Richard K. Nalugya, Aisha Kansiime, Winnifred K. Kitchen, Chenai Brenda, Wagaba Oputan, Patience Bukenya, Justine Nnakate Buregyeya, Esther Kibira, Simon P. S. |
author_sort | Ssekamatte, Tonny |
collection | PubMed |
description | BACKGROUND: Young psychoactive substance users exhibit high-risk behaviours such as unprotected sexual intercourse, and sharing needles and syringes, which increases their risk of Hepatitis B infection. However, there is limited evidence of screening, and vaccination status of this subgroup. The aim of this study was to establish the predictors of screening and completion of the hepatitis B vaccination schedule. METHODS: A cross-sectional study using respondent driven sampling was used to enrol respondents from twelve out of fifty-seven informal settlements in Kampala city. Data were collected using an electronic structured questionnaire uploaded on the KoboCollect mobile application, and analysed using Stata version 14. A “modified” Poisson regression analysis was done to determine the predictors of screening while logistic regression was used to determine the predictors of completion of the Hepatitis B vaccination schedule. RESULTS: About 13.3% (102/768) and 2.7% (21/768) of the respondents had ever screened for Hepatitis B, and completed the Hepatitis B vaccination schedule respectively. Being female (aPR 1.61, 95% CI: 1.11–2.33), earning a monthly income >USD 136 (aPR 1.78, 95% CI: 1.11–2.86); completion of the Hepatitis B vaccination schedule (aPR 1.85, 95% CI: 1.26–2.70); lack of awareness about the recommended Hepatitis B vaccine dose (aPR 0.43, 95% CI: 0.27–0.68); and the belief that the Hepatitis B vaccine is effective in preventing Hepatitis B infection (aPRR 3.67, 95% CI: 2.34–5.73) were associated with “ever screening” for Hepatitis B. Knowledge of the recommended Hepatitis B vaccine dose (aOR 0.06, 95% CI: 0.01–0.35); “ever screening” for hepatitis B (aOR 9.68, 95% CI: 2.17–43.16) and the belief that the hepatitis B vaccine is effective in preventing Hepatitis B infection (aOR 11.8, 95% CI: 1.13–110.14) were associated with completion of the hepatitis B vaccination schedule. CONCLUSIONS: Our findings indicate a low prevalence of Hepatitis B screening and completion of the Hepatitis B vaccination schedule among young psychoactive substance users in informal settings. It is evident that lack of awareness about Hepatitis B is associated with the low screening and vaccination rates. We recommend creation of awareness of Hepatitis B among young people in urban informal settlements. |
format | Online Article Text |
id | pubmed-9119510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-91195102022-05-20 Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda Ssekamatte, Tonny Isunju, John Bosco Mutyoba, Joan Nankya Tetui, Moses Mugambe, Richard K. Nalugya, Aisha Kansiime, Winnifred K. Kitchen, Chenai Brenda, Wagaba Oputan, Patience Bukenya, Justine Nnakate Buregyeya, Esther Kibira, Simon P. S. PLoS One Research Article BACKGROUND: Young psychoactive substance users exhibit high-risk behaviours such as unprotected sexual intercourse, and sharing needles and syringes, which increases their risk of Hepatitis B infection. However, there is limited evidence of screening, and vaccination status of this subgroup. The aim of this study was to establish the predictors of screening and completion of the hepatitis B vaccination schedule. METHODS: A cross-sectional study using respondent driven sampling was used to enrol respondents from twelve out of fifty-seven informal settlements in Kampala city. Data were collected using an electronic structured questionnaire uploaded on the KoboCollect mobile application, and analysed using Stata version 14. A “modified” Poisson regression analysis was done to determine the predictors of screening while logistic regression was used to determine the predictors of completion of the Hepatitis B vaccination schedule. RESULTS: About 13.3% (102/768) and 2.7% (21/768) of the respondents had ever screened for Hepatitis B, and completed the Hepatitis B vaccination schedule respectively. Being female (aPR 1.61, 95% CI: 1.11–2.33), earning a monthly income >USD 136 (aPR 1.78, 95% CI: 1.11–2.86); completion of the Hepatitis B vaccination schedule (aPR 1.85, 95% CI: 1.26–2.70); lack of awareness about the recommended Hepatitis B vaccine dose (aPR 0.43, 95% CI: 0.27–0.68); and the belief that the Hepatitis B vaccine is effective in preventing Hepatitis B infection (aPRR 3.67, 95% CI: 2.34–5.73) were associated with “ever screening” for Hepatitis B. Knowledge of the recommended Hepatitis B vaccine dose (aOR 0.06, 95% CI: 0.01–0.35); “ever screening” for hepatitis B (aOR 9.68, 95% CI: 2.17–43.16) and the belief that the hepatitis B vaccine is effective in preventing Hepatitis B infection (aOR 11.8, 95% CI: 1.13–110.14) were associated with completion of the hepatitis B vaccination schedule. CONCLUSIONS: Our findings indicate a low prevalence of Hepatitis B screening and completion of the Hepatitis B vaccination schedule among young psychoactive substance users in informal settings. It is evident that lack of awareness about Hepatitis B is associated with the low screening and vaccination rates. We recommend creation of awareness of Hepatitis B among young people in urban informal settlements. Public Library of Science 2022-05-19 /pmc/articles/PMC9119510/ /pubmed/35588113 http://dx.doi.org/10.1371/journal.pone.0267953 Text en © 2022 Ssekamatte et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Ssekamatte, Tonny Isunju, John Bosco Mutyoba, Joan Nankya Tetui, Moses Mugambe, Richard K. Nalugya, Aisha Kansiime, Winnifred K. Kitchen, Chenai Brenda, Wagaba Oputan, Patience Bukenya, Justine Nnakate Buregyeya, Esther Kibira, Simon P. S. Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda |
title | Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda |
title_full | Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda |
title_fullStr | Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda |
title_full_unstemmed | Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda |
title_short | Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda |
title_sort | predictors of hepatitis b screening and vaccination status of young psychoactive substance users in informal settlements in kampala, uganda |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119510/ https://www.ncbi.nlm.nih.gov/pubmed/35588113 http://dx.doi.org/10.1371/journal.pone.0267953 |
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