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Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly

Ebola virus (EBOV) VP35 is a polyfunctional protein involved in viral genome packaging, viral polymerase function, and host immune antagonism. The mechanisms regulating VP35’s engagement in different functions are not well-understood. We previously showed that the host E3 ubiquitin ligase TRIM6 ubiq...

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Detalles Bibliográficos
Autores principales:	van Tol, Sarah, Kalveram, Birte, Ilinykh, Philipp A., Ronk, Adam, Huang, Kai, Aguilera-Aguirre, Leopoldo, Bharaj, Preeti, Hage, Adam, Atkins, Colm, Giraldo, Maria I., Wakamiya, Maki, Gonzalez-Orozco, Maria, Warren, Abbey N., Bukreyev, Alexander, Freiberg, Alexander N., Rajsbaum, Ricardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119628/ https://www.ncbi.nlm.nih.gov/pubmed/35533195 http://dx.doi.org/10.1371/journal.ppat.1010532

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