Surfactant Protein D Influences Mortality During Abdominal Sepsis by Facilitating Escherichia coli Colonization in the Gut

Determine the role of surfactant protein D (SPD) in sepsis. DESIGN: Murine in vivo study. SETTING: Research laboratory at an academic medical center. PATIENTS: SPD knockout (SPD(−/−)) and wild-type (SPD(+/+)) mice. INTERVENTIONS: SPD(−/−) and SPD(+/+) mice were subjected to cecal ligation and punctu...

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Detalles Bibliográficos
Autores principales: Varon, Jack, Arciniegas Rubio, Antonio, Amador-Munoz, Diana, Corcoran, Alexis, DeCorte, Joseph A., Isabelle, Colleen, Pinilla Vera, Miguel, Walker, Katherine, Brown, Luke, Cernadas, Manuela, Bry, Lynn, Yang, Haopu, Kitsios, Georgios D., McVerry, Bryan J., Morris, Alison, Lee, Hyunwook, Howrylak, Judie, Englert, Joshua A., Baron, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Original Basic Science Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119639/
https://www.ncbi.nlm.nih.gov/pubmed/35620769
http://dx.doi.org/10.1097/CCE.0000000000000699

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