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Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature

A dysembryoplastic neuroepithelial tumor (DNT) is a benign neoplasm that usually occurs in the supratentorial cerebral cortex. Here, we report a rare case of an infratentorial DNT in a 42-year-old woman who presented with dizziness and a gait disturbance. Magnetic resonance imaging of the lesion dem...

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Autores principales: KAKUTA, Kiyohide, ASANO, Kenichiro, SHIMAMURA, Norihito, KUROSE, Akira, OHKUMA, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Neurosurgical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119689/
https://www.ncbi.nlm.nih.gov/pubmed/35646500
http://dx.doi.org/10.2176/jns-nmc.2021-0350
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author KAKUTA, Kiyohide
ASANO, Kenichiro
SHIMAMURA, Norihito
KUROSE, Akira
OHKUMA, Hiroki
author_facet KAKUTA, Kiyohide
ASANO, Kenichiro
SHIMAMURA, Norihito
KUROSE, Akira
OHKUMA, Hiroki
author_sort KAKUTA, Kiyohide
collection PubMed
description A dysembryoplastic neuroepithelial tumor (DNT) is a benign neoplasm that usually occurs in the supratentorial cerebral cortex. Here, we report a rare case of an infratentorial DNT in a 42-year-old woman who presented with dizziness and a gait disturbance. Magnetic resonance imaging of the lesion demonstrated hyperintensity on T2-weighted images and hypointensity on T1-weighted images of the left cerebellar hemisphere with a multifocal lesion. Macroscopically, the lesion appeared soft, avascular, and slightly torose at the cortical surface. Histologically, dysplastic disorganization of the cortex and floating neurons were observed. The pathological and immunochemical features of this case agree with the diagnosis of a DNT. The lesion partially included cortical heterotopia, which is a novel observation in an infratentorial DNT. On the basis of the previous reports, we discussed the surgical resection of the infratentorial DNT.
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spelling pubmed-91196892022-05-27 Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature KAKUTA, Kiyohide ASANO, Kenichiro SHIMAMURA, Norihito KUROSE, Akira OHKUMA, Hiroki NMC Case Rep J Case Report A dysembryoplastic neuroepithelial tumor (DNT) is a benign neoplasm that usually occurs in the supratentorial cerebral cortex. Here, we report a rare case of an infratentorial DNT in a 42-year-old woman who presented with dizziness and a gait disturbance. Magnetic resonance imaging of the lesion demonstrated hyperintensity on T2-weighted images and hypointensity on T1-weighted images of the left cerebellar hemisphere with a multifocal lesion. Macroscopically, the lesion appeared soft, avascular, and slightly torose at the cortical surface. Histologically, dysplastic disorganization of the cortex and floating neurons were observed. The pathological and immunochemical features of this case agree with the diagnosis of a DNT. The lesion partially included cortical heterotopia, which is a novel observation in an infratentorial DNT. On the basis of the previous reports, we discussed the surgical resection of the infratentorial DNT. The Japan Neurosurgical Society 2022-04-28 /pmc/articles/PMC9119689/ /pubmed/35646500 http://dx.doi.org/10.2176/jns-nmc.2021-0350 Text en © 2022 The Japan Neurosurgical Society https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives International License.
spellingShingle Case Report
KAKUTA, Kiyohide
ASANO, Kenichiro
SHIMAMURA, Norihito
KUROSE, Akira
OHKUMA, Hiroki
Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature
title Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature
title_full Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature
title_fullStr Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature
title_full_unstemmed Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature
title_short Dysembryoplastic Neuroepithelial Tumor of the Infratentorial Multiple Lesions: A Case Report and Review of the Literature
title_sort dysembryoplastic neuroepithelial tumor of the infratentorial multiple lesions: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119689/
https://www.ncbi.nlm.nih.gov/pubmed/35646500
http://dx.doi.org/10.2176/jns-nmc.2021-0350
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