Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2

INTRODUCTION: Liver-expressed antimicrobial peptide-2 (LEAP2) is an endogenous ghrelin receptor antagonist, which is upregulated in the fed state and downregulated during fasting. We hypothesized that the ketone body beta-hydroxybutyrate (BHB) is involved in the downregulation of LEAP2 during condit...

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Detalles Bibliográficos
Autores principales: Holm, Stephanie, Husted, Anna S, Skov, Louise J, Morville, Thomas H, Hagemann, Christoffer A, Jorsal, Tina, Dall, Morten, Jakobsen, Alexander, Klein, Anders B, Treebak, Jonas T, Knop, Filip K, Schwartz, Thue W, Clemmensen, Christoffer, Holst, Birgitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119693/
https://www.ncbi.nlm.nih.gov/pubmed/35352108
http://dx.doi.org/10.1210/endocr/bqac038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119693/
https://www.ncbi.nlm.nih.gov/pubmed/35352108
http://dx.doi.org/10.1210/endocr/bqac038

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