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Beta-Hydroxybutyrate Suppresses Hepatic Production of the Ghrelin Receptor Antagonist LEAP2
INTRODUCTION: Liver-expressed antimicrobial peptide-2 (LEAP2) is an endogenous ghrelin receptor antagonist, which is upregulated in the fed state and downregulated during fasting. We hypothesized that the ketone body beta-hydroxybutyrate (BHB) is involved in the downregulation of LEAP2 during condit...
Autores principales: | Holm, Stephanie, Husted, Anna S, Skov, Louise J, Morville, Thomas H, Hagemann, Christoffer A, Jorsal, Tina, Dall, Morten, Jakobsen, Alexander, Klein, Anders B, Treebak, Jonas T, Knop, Filip K, Schwartz, Thue W, Clemmensen, Christoffer, Holst, Birgitte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119693/ https://www.ncbi.nlm.nih.gov/pubmed/35352108 http://dx.doi.org/10.1210/endocr/bqac038 |
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