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MLL1 Inhibition and Vitamin D Signaling Cooperate to Facilitate the Expanded Pluripotency State
Dynamic establishment of histone modifications in early development coincides with programed cell fate restriction and loss of totipotency beyond the early blastocyst stage. Causal function of histone-modifying enzymes in this process remains to be defined. Here we show that inhibiting histone methy...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119704/ https://www.ncbi.nlm.nih.gov/pubmed/31775036 http://dx.doi.org/10.1016/j.celrep.2019.10.074 |