Cargando…

Fibroblasts in Scar Formation: Biology and Clinical Translation

Scarring, which develops due to fibroblast activation and excessive extracellular matrix deposition, can cause physical, psychological, and cosmetic problems. Fibroblasts are the main type of connective tissue cells and play important roles in wound healing. However, the underlying mechanisms of fib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Huan, Shan, Yihan, Gong, Ruicheng, Lin, Danfeng, Zhang, Mengwen, Wang, Chen, Wang, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119755/ https://www.ncbi.nlm.nih.gov/pubmed/35602101 http://dx.doi.org/10.1155/2022/4586569

Ejemplares similares

Mechanism of action and therapeutic effects of oxidative stress and stem cell-based materials in skin aging: Current evidence and future perspectives
por: Qian, Huan, et al.
Publicado: (2023)

Retracted: Fibroblasts in Scar Formation: Biology and Clinical Translation
por: Longevity, Oxidative Medicine and Cellular
Publicado: (2023)

The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation
por: Moretti, Leandro, et al.
Publicado: (2021)

Fibrotic Scar in CNS Injuries: From the Cellular Origins of Fibroblasts to the Molecular Processes of Fibrotic Scar Formation
por: Ayazi, Maryam, et al.
Publicado: (2022)

Clinic Reopening Post-Coronavirus Disease 2019: Precaution of a Plastic Surgery Clinic in China
por: Wang, Lu, et al.
Publicado: (2020)

Effect of THBS1 on the Biological Function of Hypertrophic Scar Fibroblasts
por: Jiang, D., et al.
Publicado: (2020)

Effect of Mortalin on Scar Formation in Human Dermal Fibroblasts and a Rat Incisional Scar Model
por: Jung, Bok Ki, et al.
Publicado: (2022)

The Japanese Experience with Basic Fibroblast Growth Factor in Cutaneous Wound Management and Scar Prevention: A Systematic Review of Clinical and Biological Aspects
por: Abdelhakim, Mohamed, et al.
Publicado: (2020)

Paclitaxel reduces formation of hypertrophic scars in the rabbit ear model
por: Huang, Li-ping, et al.
Publicado: (2015)

Specialized fibroblast differentiated states underlie scar formation in the infarcted mouse heart
por: Fu, Xing, et al.
Publicado: (2018)

The role of macrophages in the formation of hypertrophic scars and keloids
por: Xu, Xiangwen, et al.
Publicado: (2020)

Interleukin-10-Modified Adipose-Derived Mesenchymal Stem Cells Prevent Hypertrophic Scar Formation via Regulating the Biological Characteristics of Fibroblasts and Inflammation
por: Xie, Fang, et al.
Publicado: (2022)

Shikonin promotes hypertrophic scar repair by autophagy of hypertrophic scar-derived fibroblasts
por: Zhang, Qing, et al.
Publicado: (2023)

Inhibition of sphingosine kinase 2 attenuates hypertrophic scar formation via upregulation of Smad7 in human hypertrophic scar fibroblasts
por: Zeng, Jian, et al.
Publicado: (2020)

Nonsteroidal Anti-Inflammatory Drugs for Wounds: Pain Relief or Excessive Scar Formation?
por: Su, Wen-Hsiang, et al.
Publicado: (2010)

Characterization of the skin keloid microenvironment
por: Zhang, Mengwen, et al.
Publicado: (2023)

Scars or Regeneration?—Dermal Fibroblasts as Drivers of Diverse Skin Wound Responses
por: Jiang, Dongsheng, et al.
Publicado: (2020)

Control of Scar Tissue Formation in the Cornea: Strategies in Clinical and Corneal Tissue Engineering
por: Wilson, Samantha L., et al.
Publicado: (2012)

Role of Mitogen-Activated Protein Kinases in the Formation of Hypertrophic Scar with Model of Lipopolysaccharide Stimulated Skin Fibroblast Cells
por: Wang, Weidong, et al.
Publicado: (2018)

Mechanotransduction in skin wound healing and scar formation: Potential therapeutic targets for controlling hypertrophic scarring
por: Yin, Jiayi, et al.
Publicado: (2022)

Activin B signaling may promote the conversion of normal fibroblasts to scar fibroblasts
por: Deng, Shi-Kang, et al.
Publicado: (2020)

Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction †
por: Curaj, Adelina, et al.
Publicado: (2020)

Narrative review of the mechanism of natural products and scar formation in wound repair
por: Wan, Xiaoping, et al.
Publicado: (2022)

Fibrogenic fibroblast-selective near-infrared phototherapy to control scarring
por: Chen, Zelin, et al.
Publicado: (2019)

Molecular mechanisms of uterine incision healing and scar formation
por: Sun, Qing, et al.
Publicado: (2023)

Mechanisms underlying pathological scarring by fibroblasts during wound healing
por: Ma, Yizhao, et al.
Publicado: (2023)

Methods for the Assessment of NET Formation: From Neutrophil Biology to Translational Research
por: Stoimenou, Marina, et al.
Publicado: (2022)

Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin
por: Jiang, Dongsheng, et al.
Publicado: (2020)

Hydroxycamptothecin regulates scar formation of the filtration channel under scleral flap by inhibiting the proliferation of scleral fibroblasts
por: Gu, Hongwei, et al.
Publicado: (2023)

Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing
por: Hesketh, Mark, et al.
Publicado: (2017)

SPARC is expressed in scars of the Tenon’s capsule and mediates scarring properties of human Tenon’s fibroblasts in vitro
por: Fuchshofer, Rudolf, et al.
Publicado: (2011)

Effects of Factors Influencing Scar Formation on the Scar Microbiome in Patients with Burns
por: Jung, Yeongyun, et al.
Publicado: (2023)

The role of altered fatty acid in pathological scars and their dermal fibroblasts
por: Yang, Jin-Xiu, et al.
Publicado: (2022)

HDAC5-mediated Smad7 silencing through MEF2A is critical for fibroblast activation and hypertrophic scar formation
por: Gao, Ya, et al.
Publicado: (2022)

Effect of FK506 in reducing scar formation by inducing fibroblast apoptosis after sciatic nerve injury in rats
por: Que, J, et al.
Publicado: (2013)

Curcumin-induced fibroblast apoptosis and in vitro wound contraction are regulated by antioxidants and heme oxygenase: implications for scar formation
por: Scharstuhl, A, et al.
Publicado: (2009)

Biologicals and Fetal Cell Therapy for Wound and Scar Management
por: Hirt-Burri, Nathalie, et al.
Publicado: (2011)

Recent Advances in Scar Biology
por: Ogawa, Rei
Publicado: (2018)

Oxymatrine promotes hypertrophic scar repair through reduced human scar fibroblast viability, collagen and induced apoptosis via autophagy inhibition
por: Deng, Xingwang, et al.
Publicado: (2021)

The molecular biology of pancreatic adenocarcinoma: translational challenges and clinical perspectives
por: Wang, Shun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ooan37i48t59kg88rs1oeha9lr