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URB597 and Andrographolide Improve Brain Microvascular Endothelial Cell Permeability and Apoptosis by Reducing Oxidative Stress and Inflammation Associated with Activation of Nrf2 Signaling in Oxygen-Glucose Deprivation

Ischemic stroke, a cerebrovascular disease worldwide, triggers a cascade of pathophysiological events, including blood-brain barrier (BBB) breakdown. Brain microvascular endothelial cells (BMECs) play a vital role in maintaining BBB function. The injury of BMECs may worsen neurovascular dysfunction...

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Detalles Bibliográficos
Autores principales:	Wang, Da-Peng, Kang, Kai, Sun, Jun, Lin, Qi, Lv, Qiao-Li, Hai, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119762/ https://www.ncbi.nlm.nih.gov/pubmed/35602108 http://dx.doi.org/10.1155/2022/4139330

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