Cargando…
Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients
INTRODUCTION: Non-variceal upper gastrointestinal hemorrhage (NVUGIH) often leads to systematic hospitalization and emergency endoscopy. However, in most cases, it does not constitute an immediate life threat. This study aimed to evaluate the Glasgow-Blatchford Score (GBS) in predicting the need for...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119816/ https://www.ncbi.nlm.nih.gov/pubmed/35600194 http://dx.doi.org/10.1016/j.amsu.2022.103778 |
_version_ | 1784710774490398720 |
---|---|
author | Maghrebi, Houcine Beji, Hazem Haddad, Anis Sebai, Amine Safraoui, Samia Hafi, Maroua Laabidi, Asma Jouini, Mohamed Kacem, Montasser Jamel |
author_facet | Maghrebi, Houcine Beji, Hazem Haddad, Anis Sebai, Amine Safraoui, Samia Hafi, Maroua Laabidi, Asma Jouini, Mohamed Kacem, Montasser Jamel |
author_sort | Maghrebi, Houcine |
collection | PubMed |
description | INTRODUCTION: Non-variceal upper gastrointestinal hemorrhage (NVUGIH) often leads to systematic hospitalization and emergency endoscopy. However, in most cases, it does not constitute an immediate life threat. This study aimed to evaluate the Glasgow-Blatchford Score (GBS) in predicting the need for transfusions, and/or endoscopic or surgical treatments. MATERIALS AND METHODS: We conducted a retrospective monocentric study including 91 patients admitted in the general surgery department of the Hospital La Rabta Tunis for a NVUGIH. Univariate analysis was performed with the Student t-test for continuous variables and with the Chi-square test for categorical variables. For a cut-off point of 9, we calculated the sensibility and the sensitivity of the GBS to predict the need for transfusions and/or hemostatic procedure. RESULTS: During the study period, 91 patients were admitted for NVUGIH. Sixty-one patients (67%) were transfused. Seven patients (7.7%) underwent emergency surgery and two patients had endoscopic hemostasis. The predictive factors for the use of transfusion and/or hemostasic treatments were: Age >50 years, ASA score, HR ≥ 90 bpm, pallor, Hb ≤ 9,5 g/dl, Urea ≥9,7 mmol/L. For a cut-off of 9 points of the GBS, sensitivity was 85.71% and specificity 92.86%. The positive predictive value was 96%. The negative predictive value was 74%. CONCLUSION: The main interest of the GBS lies in dispatching the patients between intensive care units for therapeutic intervention (if GBS> = 9) and ordinary hospitalization for surveillance (if GBS <9). It then makes it possible to rationalize the management of patients with digestive hemorrhage to identify those requiring hospital treatments (transfusion, endoscopic treatment, or surgery). |
format | Online Article Text |
id | pubmed-9119816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-91198162022-05-21 Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients Maghrebi, Houcine Beji, Hazem Haddad, Anis Sebai, Amine Safraoui, Samia Hafi, Maroua Laabidi, Asma Jouini, Mohamed Kacem, Montasser Jamel Ann Med Surg (Lond) Case Series INTRODUCTION: Non-variceal upper gastrointestinal hemorrhage (NVUGIH) often leads to systematic hospitalization and emergency endoscopy. However, in most cases, it does not constitute an immediate life threat. This study aimed to evaluate the Glasgow-Blatchford Score (GBS) in predicting the need for transfusions, and/or endoscopic or surgical treatments. MATERIALS AND METHODS: We conducted a retrospective monocentric study including 91 patients admitted in the general surgery department of the Hospital La Rabta Tunis for a NVUGIH. Univariate analysis was performed with the Student t-test for continuous variables and with the Chi-square test for categorical variables. For a cut-off point of 9, we calculated the sensibility and the sensitivity of the GBS to predict the need for transfusions and/or hemostatic procedure. RESULTS: During the study period, 91 patients were admitted for NVUGIH. Sixty-one patients (67%) were transfused. Seven patients (7.7%) underwent emergency surgery and two patients had endoscopic hemostasis. The predictive factors for the use of transfusion and/or hemostasic treatments were: Age >50 years, ASA score, HR ≥ 90 bpm, pallor, Hb ≤ 9,5 g/dl, Urea ≥9,7 mmol/L. For a cut-off of 9 points of the GBS, sensitivity was 85.71% and specificity 92.86%. The positive predictive value was 96%. The negative predictive value was 74%. CONCLUSION: The main interest of the GBS lies in dispatching the patients between intensive care units for therapeutic intervention (if GBS> = 9) and ordinary hospitalization for surveillance (if GBS <9). It then makes it possible to rationalize the management of patients with digestive hemorrhage to identify those requiring hospital treatments (transfusion, endoscopic treatment, or surgery). Elsevier 2022-05-13 /pmc/articles/PMC9119816/ /pubmed/35600194 http://dx.doi.org/10.1016/j.amsu.2022.103778 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Series Maghrebi, Houcine Beji, Hazem Haddad, Anis Sebai, Amine Safraoui, Samia Hafi, Maroua Laabidi, Asma Jouini, Mohamed Kacem, Montasser Jamel Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients |
title | Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients |
title_full | Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients |
title_fullStr | Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients |
title_full_unstemmed | Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients |
title_short | Risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the Glasgow-Blatchford score: A case series of 91 patients |
title_sort | risk stratifying patients with non-varicosic upper gastrointestinal hemorrhage using the glasgow-blatchford score: a case series of 91 patients |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119816/ https://www.ncbi.nlm.nih.gov/pubmed/35600194 http://dx.doi.org/10.1016/j.amsu.2022.103778 |
work_keys_str_mv | AT maghrebihoucine riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT bejihazem riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT haddadanis riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT sebaiamine riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT safraouisamia riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT hafimaroua riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT laabidiasma riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT jouinimohamed riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients AT kacemmontasserjamel riskstratifyingpatientswithnonvaricosicuppergastrointestinalhemorrhageusingtheglasgowblatchfordscoreacaseseriesof91patients |