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Cellular redox imbalance on the crossroad between mitochondrial dysfunction, senescence, and proliferation
Recent studies demonstrate that redox imbalance of NAD(+)/NADH and NADP(+)/NADPH pairs due to impaired respiration may trigger two “hidden” metabolic pathways on the crossroad between mitochondrial dysfunction, senescence, and proliferation: “β-oxidation shuttle” and “hydride transfer complex (HTC)...
Autores principales: | Bakalova, Rumiana, Aoki, Ichio, Zhelev, Zhivko, Higashi, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119829/ https://www.ncbi.nlm.nih.gov/pubmed/35584568 http://dx.doi.org/10.1016/j.redox.2022.102337 |
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