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Human induced mesenchymal stem cells display increased sensitivity to matrix stiffness

The clinical translation of mesenchymal stem cells (MSCs) is limited by population heterogeneity and inconsistent responses to engineered signals. Specifically, the extent in which MSCs respond to mechanical cues varies significantly across MSC lines. Although induced pluripotent stem cells (iPSCs)...

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Detalles Bibliográficos
Autores principales: Gultian, Kirstene A., Gandhi, Roshni, Sarin, Khushi, Sladkova-Faure, Martina, Zimmer, Matthew, de Peppo, Giuseppe Maria, Vega, Sebastián L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119934/
https://www.ncbi.nlm.nih.gov/pubmed/35589731
http://dx.doi.org/10.1038/s41598-022-12143-2