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Estradiol-mediated inhibition of DNMT1 decreases p53 expression to induce M2-macrophage polarization in lung cancer progression

Previous studies indicate that estrogen positively regulates lung cancer progression. Understanding the reasons will be beneficial for treating women with lung cancer in the future. In this study, we found that tumor formation was more significant in female EGFR(L858R) mice than in male mice. P53 ex...

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Detalles Bibliográficos
Autores principales:	Chen, Yung-Ching, Young, Ming-Jer, Chang, Hui-Ping, Liu, Chia-Yu, Lee, Chia-Chi, Tseng, Yau-Lin, Wang, Yi-Ching, Chang, Wen-Chang, Hung, Jan-Jong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119954/ https://www.ncbi.nlm.nih.gov/pubmed/35589688 http://dx.doi.org/10.1038/s41389-022-00397-4

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