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Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT

OBJECTIVE: To examine the association between COVID-19 impact and clinical outcomes of an integrated collaborative care intervention for adults with obesity and comorbid depression. METHODS: Latent class analysis identified clusters of self-reported COVID-19 impact. Cluster characteristics were exam...

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Autores principales: Kringle, Emily A., Lv, Nan, Ronneberg, Corina R., Wittels, Nancy, Rosas, Lisa G., Steinman, Lesley E., Smyth, Joshua M., Gerber, Ben S., Xiao, Lan, Venditti, Elizabeth M., Ajilore, Olusola A., Williams, Leanne M., Ma, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119961/
https://www.ncbi.nlm.nih.gov/pubmed/35644753
http://dx.doi.org/10.1016/j.orcp.2022.05.005
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author Kringle, Emily A.
Lv, Nan
Ronneberg, Corina R.
Wittels, Nancy
Rosas, Lisa G.
Steinman, Lesley E.
Smyth, Joshua M.
Gerber, Ben S.
Xiao, Lan
Venditti, Elizabeth M.
Ajilore, Olusola A.
Williams, Leanne M.
Ma, Jun
author_facet Kringle, Emily A.
Lv, Nan
Ronneberg, Corina R.
Wittels, Nancy
Rosas, Lisa G.
Steinman, Lesley E.
Smyth, Joshua M.
Gerber, Ben S.
Xiao, Lan
Venditti, Elizabeth M.
Ajilore, Olusola A.
Williams, Leanne M.
Ma, Jun
author_sort Kringle, Emily A.
collection PubMed
description OBJECTIVE: To examine the association between COVID-19 impact and clinical outcomes of an integrated collaborative care intervention for adults with obesity and comorbid depression. METHODS: Latent class analysis identified clusters of self-reported COVID-19 impact. Cluster characteristics were examined using Fishers’ least significant difference method and canonical discriminant analysis. Intervention vs. usual care effects on primary (body mass index [BMI], depressive symptoms) and secondary (anxiety symptoms and other psychosocial) outcomes stratified by cluster were examined using linear mixed models. RESULTS: Three clusters were identified: mental health and sleep impact (cluster 1, n = 37), economic impact (cluster 2, n = 18), and less overall impact (cluster 3, n = 20). Clusters differed in age, income, diet, and baseline coping skills. The intervention led to improvements across several health outcomes compared with usual care, with medium to large effects on functional impairments (standardized mean difference, −0.7 [95% CI: −1.3, −0.1]) in cluster 1, depressive symptoms (−1.1 [95% CI: −2.0, −0.1]) and obesity-related problems (−1.6 [95% CI: −2.8, −0.4]) in cluster 2, and anxiety (−1.1 [95% CI: −1.9, −0.3]) in cluster 3. CONCLUSIONS: People with obesity and comorbid depression may have varied intervention responses based on COVID-19 impact. Interventions tailored to specific COVID-19 impact clusters may restore post-pandemic health.
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spelling pubmed-91199612022-05-20 Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT Kringle, Emily A. Lv, Nan Ronneberg, Corina R. Wittels, Nancy Rosas, Lisa G. Steinman, Lesley E. Smyth, Joshua M. Gerber, Ben S. Xiao, Lan Venditti, Elizabeth M. Ajilore, Olusola A. Williams, Leanne M. Ma, Jun Obes Res Clin Pract Article OBJECTIVE: To examine the association between COVID-19 impact and clinical outcomes of an integrated collaborative care intervention for adults with obesity and comorbid depression. METHODS: Latent class analysis identified clusters of self-reported COVID-19 impact. Cluster characteristics were examined using Fishers’ least significant difference method and canonical discriminant analysis. Intervention vs. usual care effects on primary (body mass index [BMI], depressive symptoms) and secondary (anxiety symptoms and other psychosocial) outcomes stratified by cluster were examined using linear mixed models. RESULTS: Three clusters were identified: mental health and sleep impact (cluster 1, n = 37), economic impact (cluster 2, n = 18), and less overall impact (cluster 3, n = 20). Clusters differed in age, income, diet, and baseline coping skills. The intervention led to improvements across several health outcomes compared with usual care, with medium to large effects on functional impairments (standardized mean difference, −0.7 [95% CI: −1.3, −0.1]) in cluster 1, depressive symptoms (−1.1 [95% CI: −2.0, −0.1]) and obesity-related problems (−1.6 [95% CI: −2.8, −0.4]) in cluster 2, and anxiety (−1.1 [95% CI: −1.9, −0.3]) in cluster 3. CONCLUSIONS: People with obesity and comorbid depression may have varied intervention responses based on COVID-19 impact. Interventions tailored to specific COVID-19 impact clusters may restore post-pandemic health. Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. 2022 2022-05-20 /pmc/articles/PMC9119961/ /pubmed/35644753 http://dx.doi.org/10.1016/j.orcp.2022.05.005 Text en © 2022 Asia Oceania Association for the Study of Obesity. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Kringle, Emily A.
Lv, Nan
Ronneberg, Corina R.
Wittels, Nancy
Rosas, Lisa G.
Steinman, Lesley E.
Smyth, Joshua M.
Gerber, Ben S.
Xiao, Lan
Venditti, Elizabeth M.
Ajilore, Olusola A.
Williams, Leanne M.
Ma, Jun
Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT
title Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT
title_full Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT
title_fullStr Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT
title_full_unstemmed Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT
title_short Association of COVID-19 impact with outcomes of an integrated obesity and depression intervention: Posthoc analysis of an RCT
title_sort association of covid-19 impact with outcomes of an integrated obesity and depression intervention: posthoc analysis of an rct
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119961/
https://www.ncbi.nlm.nih.gov/pubmed/35644753
http://dx.doi.org/10.1016/j.orcp.2022.05.005
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