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Cancer associated fibroblast–derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis

Cancer-associated fibroblasts (CAFs) are one of the most enriched components of Hepatocellular carcinoma (HCC) microenvironment, which are tightly related to the metastasis and invasion of HCC. We identified a mechanism by which CAF-derived chemokine CCL5 enhanced HCC metastasis by triggering the HI...

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Detalles Bibliográficos
Autores principales:	Xu, Haixu, Zhao, Jie, Li, Jinping, Zhu, Zhifeng, Cui, Zhaohai, Liu, Ran, Lu, Rong, Yao, Zhi, Xu, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9119971/ https://www.ncbi.nlm.nih.gov/pubmed/35589690 http://dx.doi.org/10.1038/s41419-022-04935-1

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